Bumetanide

ATC Code C03CA02

Bumetanide

Definition

A potent sulfamoylanthranilic acid derivative belonging to the class of loop diuretics. In the brain, bumetanide may prevent seizures in neonates by blocking the bumetanide-sensitive sodium-potassium-chloride cotransporter (NKCC1), thereby inhibiting chloride uptake thus, decreasing the internal chloride concentration in neurons and may block the excitatory effect of GABA in neonates.

Also known as BUMETANIDE, Bumex, Burinex, Edemex — per NCIT

Also identified as

Indications

Disease Relation Source
Acute kidney injury may treat MEDRT · Public domain (U.S. Government work)
Chronic kidney disease may treat MEDRT · Public domain (U.S. Government work)
Cirrhosis may treat MEDRT · Public domain (U.S. Government work)
Heart failure may treat MEDRT · Public domain (U.S. Government work)
Hypertensive disorder may treat MEDRT · Public domain (U.S. Government work)
Nephrotic syndrome may treat MEDRT · Public domain (U.S. Government work)
Pulmonary edema may treat MEDRT · Public domain (U.S. Government work)

Organ Effects

Organ Side effect / interaction Source
Adult mammalian kidney may treat a disease of this organ DERIVED · CC BY 4.0
Alimentary part of gastrointestinal system may treat a disease of this organ DERIVED · CC BY 4.0
Cardiovascular system may treat a disease of this organ DERIVED · CC BY 4.0
Genitourinary system may treat a disease of this organ DERIVED · CC BY 4.0
Heart may treat a disease of this organ DERIVED · CC BY 4.0
Liver may treat a disease of this organ DERIVED · CC BY 4.0
Lungs may treat a disease of this organ DERIVED · CC BY 4.0
Renal system may treat a disease of this organ DERIVED · CC BY 4.0
Respiratory system may treat a disease of this organ DERIVED · CC BY 4.0

9 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.