Rivaroxaban

Definition

An orally bioavailable oxazolidinone derivative and direct inhibitor of the coagulation factor Xa with anticoagulant activity. Upon oral administration, rivaroxaban selectively binds to both free factor Xa and factor Xa bound in the prothrombinase complex. This interferes with the conversion of prothrombin (factor II) to thrombin and eventually prevents the formation of cross-linked fibrin clots. Rivaroxaban does not affect existing thrombin levels.

NCIT:C77995 · NCI Thesaurus OBO Edition · CC BY 4.0

Also known as 5-Chloro-N-(((5S)-2-oxo-3-(4-(3-oxomorpholin-4-yl)phenyl)- 1,3-oxazolidin-5-yl)methyl)thiophene-2-carboxamide, BAY 59 7939, BAY 59-7939, BAY 597939, BAY-59-7939, BAY597939, RIVAROXABAN, Xarelto — per NCIT

Also identified as

ATC B01AF per NCIT
NCIT NCIT:C77995 per NCIT

Indications

Disease	Relation	Source
Pulmonary embolism	may prevent	MEDRT · Public domain (U.S. Government work)
Stroke	may prevent	MEDRT · Public domain (U.S. Government work)
Pulmonary embolism	may treat	MEDRT · Public domain (U.S. Government work)

Organ Effects

Organ	Side effect / interaction	Source
Cardiovascular system	may treat a disease of this organ	DERIVED · CC BY 4.0

1 entry above is marked DERIVED: Atlas Médico inferred it by combining two sourced claims, and no source asserts this link directly. Treat it as a navigation aid, not as a clinical statement.