Carboprost

Definition

The (15S)-15 methyl analogue of naturally occurring prostaglandin F2 alpha (PGF2 alpha) with oxytocic activity. Mimicking endogenous PGF2 alpha, carboprost activates prostaglandin F receptor, a G-protein coupled receptor, on smooth muscle cells, thereby resulting in smooth muscle contractions. When administered intramuscularly on gravid subjects, this agent induces myometrium contractions, thereby initiating luteolysis and consequently parturition. Furthermore, carboprost's action on vascular smooth muscle and gastrointestinal tract sphincters leads to raised blood pressure and induces vomiting or diarrhea, respectively.

NCIT:C61662 · NCI Thesaurus OBO Edition · CC BY 4.0

Also known as (15S)-15-Methyl-PGF2alpha, CARBOPROST, Methyl-PGF2-alpha, Prostin 15M, U 32921 — per NCIT

Also identified as

ATC G02AD04 per RXNORM
NCIT NCIT:C61662 per NCIT
SCTID 109057004 per RXNORM
SCTID 373455002 per RXNORM
UNII 7B5032XT6O per RXNORM

Indications

Disease	Relation	Source
Cystitis	may treat	MEDRT · Public domain (U.S. Government work)

Organ Effects

Organ	Side effect / interaction	Source
Genitourinary system	may treat a disease of this organ	DERIVED · CC BY 4.0
Renal system	may treat a disease of this organ	DERIVED · CC BY 4.0
Urinary bladder	may treat a disease of this organ	DERIVED · CC BY 4.0

3 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.