Cefotaxime

ATC Code J01DD01

Cefotaxime

Definition

A third generation semisynthetic cephalosporin antibiotic with bactericidal activity. Cefotaxime inhibits mucopeptide synthesis by binding to and inactivating penicillin binding proteins thereby interfering with the final transpeptidation step required for cross-linking of peptidoglycan units which are a component of bacterial cell walls. This results in a reduction of cell wall stability and causes cell lysis.

Also known as CEFOTAXIME — per NCIT

Also identified as

Indications

Disease Relation Source
Acinetobacter infectious disease may treat MEDRT · Public domain (U.S. Government work)
Bacterial meningitis may treat MEDRT · Public domain (U.S. Government work)
Bacterial pneumonia may treat MEDRT · Public domain (U.S. Government work)
Bacteroides infectious disease may treat MEDRT · Public domain (U.S. Government work)
Clostridium infectious disease may treat MEDRT · Public domain (U.S. Government work)
Escherichia coli infection may treat MEDRT · Public domain (U.S. Government work)
Gonorrhea may treat MEDRT · Public domain (U.S. Government work)
Haemophilus infectious disease may treat MEDRT · Public domain (U.S. Government work)
Klebsiella infectious disease may treat MEDRT · Public domain (U.S. Government work)
Pelvic inflammatory disease may treat MEDRT · Public domain (U.S. Government work)
Peritonitis may treat MEDRT · Public domain (U.S. Government work)
Proteus infectious disease may treat MEDRT · Public domain (U.S. Government work)
Pseudomonas infection may treat MEDRT · Public domain (U.S. Government work)
Salmonellosis may treat MEDRT · Public domain (U.S. Government work)
Skin disease caused by bacterial infection may treat MEDRT · Public domain (U.S. Government work)
Staphylococcal infection may treat MEDRT · Public domain (U.S. Government work)
Streptococcal infection may treat MEDRT · Public domain (U.S. Government work)
Urinary tract infection may treat MEDRT · Public domain (U.S. Government work)

Organ Effects

Organ Side effect / interaction Source
Central nervous system may treat a disease of this organ DERIVED · CC BY 4.0
Female reproductive system may treat a disease of this organ DERIVED · CC BY 4.0
Genitourinary system may treat a disease of this organ DERIVED · CC BY 4.0
Lungs may treat a disease of this organ DERIVED · CC BY 4.0
Meninx may treat a disease of this organ DERIVED · CC BY 4.0
Nervous system may treat a disease of this organ DERIVED · CC BY 4.0
Reproductive system may treat a disease of this organ DERIVED · CC BY 4.0
Respiratory system may treat a disease of this organ DERIVED · CC BY 4.0

8 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.