Cefotetan

ATC Code J01DC05

Cefotetan

Definition

A semi-synthetic, broad-spectrum, beta-lactamase-resistant, second-generation cephalosporin antibiotic derived from cephalosporium. The bactericidal activity of cefotetan disodium is caused by an inhibition of bacterial cell wall synthesis via inhibition of cross-linking of peptidoglycans. This results in a reduction of cell wall stability and causes cell lysis. Cefotetan disodium is more active against gram-negative organisms and less active against gram-positive organisms compared to first-generation cephalosporins.

Also known as CEFOTETAN, ICI 156,834, ICI-156834 — per NCIT

Also identified as

Indications

Disease Relation Source
Abscess may treat MEDRT · Public domain (U.S. Government work)
Bacteroides infectious disease may treat MEDRT · Public domain (U.S. Government work)
Clostridium infectious disease may treat MEDRT · Public domain (U.S. Government work)
Escherichia coli infection may treat MEDRT · Public domain (U.S. Government work)
Gonorrhea may treat MEDRT · Public domain (U.S. Government work)
Haemophilus infectious disease may treat MEDRT · Public domain (U.S. Government work)
Klebsiella infectious disease may treat MEDRT · Public domain (U.S. Government work)
Peritonitis may treat MEDRT · Public domain (U.S. Government work)
Proteus infectious disease may treat MEDRT · Public domain (U.S. Government work)
Respiratory tract infectious disorder may treat MEDRT · Public domain (U.S. Government work)
Skin disease caused by bacterial infection may treat MEDRT · Public domain (U.S. Government work)
Staphylococcal infection may treat MEDRT · Public domain (U.S. Government work)
Streptococcal infection may treat MEDRT · Public domain (U.S. Government work)
Urinary tract infection may treat MEDRT · Public domain (U.S. Government work)