Chlorhexidine
Chlorhexidine
Definition
A biguanide compound used as an antiseptic agent with topical antibacterial activity. Chlorhexidine is positively charged and reacts with the negatively charged microbial cell surface, thereby destroying the integrity of the cell membrane. Subsequently, chlorhexidine penetrates into the cell and causes leakage of intracellular components leading to cell death. Since gram positive bacteria are more negatively charged, they are more sensitive to this agent.
Also known as CHLORHEXIDINE — per NCIT
Also identified as
- ATC A01AB03 per RXNORM
- ATC B05CA02 per RXNORM
- ATC D08AC02 per RXNORM
- ATC D09AA12 per RXNORM
- ATC R02AA05 per RXNORM
- ATC S01AX09 per RXNORM
- ATC S02AA09 per RXNORM
- ATC S03AA04 per RXNORM
- NCIT NCIT:C364 per NCIT
- SCTID 373568007 per RXNORM
- SCTID 96316004 per RXNORM
- UNII R4KO0DY52L per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Gram-negative bacterial infections | may treat | MEDRT · Public domain (U.S. Government work) |
| Gram-positive bacterial infections | may treat | MEDRT · Public domain (U.S. Government work) |
| Oral candidiasis | may treat | MEDRT · Public domain (U.S. Government work) |
| Periodontal disorder | may treat | MEDRT · Public domain (U.S. Government work) |
| Skin disorder caused by infection | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Calcareous tooth | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Craniocervical region | may treat a disease of this organ | DERIVED · CC BY 4.0 |
2 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.