Chlorpheniramine Polistirex
Chlorpheniramine Polistirex
Definition
A complex of the synthetic alkylamine derivative and histamine-1 (H1) receptor antagonist chlorpheniramine with sulfonated styrene-divinylbenzene copolymer, with anti-allergic activity. Upon administration, chlorpheniramine competitively blocks the H1 receptor, thereby preventing the actions of histamine on capillaries, and the resulting vasodilation and edema of the respiratory mucosa. Chlorpheniramine also displays anticholinergic and mild sedative effects.
Also known as 3-(p-Chlorophenyl)-3-(2-pyridyl)-N,N-dimethylpropylamine, 4-Chloropheniramine, Allergican, Allergisan, Chloropheniramine, Chlorophenylpyridamine, Chloropiril, Chlorphenamine, CHLORPHENIRAMINE, Chlorpheniramine Polistirex, Chlorprophenpyridamine, Haynon, Hayon, Histadur, Polaronil — per NCIT
Also identified as
- ATC R06AB04 per RXNORM
- NCIT NCIT:C61672 per NCIT
- SCTID 372914003 per RXNORM
- SCTID 9944001 per RXNORM
- UNII 3U6IO1965U per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Perennial allergic rhinitis | may treat | MEDRT · Public domain (U.S. Government work) |
| Urticaria | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Craniocervical region | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Nasal cavity | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Skin of body | may treat a disease of this organ | DERIVED · CC BY 4.0 |
3 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.