Citalopram
Citalopram
Definition
A bicyclic phthalene derivative and selective serotonin reuptake inhibitor (SSRI), with antidepressant and anxiolytic activities. Citalopram selectively inhibits the neuronal reuptake of the neurotransmitter serotonin (5-HT) in presynaptic cells in the central nervous system, thereby increasing levels of 5-HT within the synaptic cleft and enhancing the actions of serotonin on its receptors. Increased serotonergic neurotransmission results in antidepressive and anxiolytic effects.
Also known as 1,3-Dihydro-1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-5-isobenzofurancarbonitrile, Cipram, CITALOPRAM, Lu 10-171, Nitalapram — per NCIT
Also identified as
- ATC N06AB04 per RXNORM
- NCIT NCIT:C61680 per NCIT
- SCTID 321986007 per RXNORM
- SCTID 372596005 per RXNORM
- UNII 0DHU5B8D6V per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Alcohol abuse | may treat | MEDRT · Public domain (U.S. Government work) |
| Dementia | may treat | MEDRT · Public domain (U.S. Government work) |
| Depressive disorder | may treat | MEDRT · Public domain (U.S. Government work) |
| Diabetic neuropathy | may treat | MEDRT · Public domain (U.S. Government work) |
| Nicotine dependence | may treat | MEDRT · Public domain (U.S. Government work) |
| Obsessive-compulsive disorder | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Central nervous system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Nervous system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
2 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.