Clozapine
ATC Code
N05AH02
Clozapine
Definition
A synthetic dibenzo-diazepine derivative, atypical antipsychotic Clozapine blocks several neurotransmitter receptors in the brain (dopamine type 4, serotonin type 2, norepinephrine, acetylcholine, and histamine receptors). Unlike traditional antipsychotic agents, it weakly blocks dopamine type 2 receptors. It relieves schizophrenic symptoms (hallucinations, delusions, dementia). (NCI04)
Also known as 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine, CLOZAPINE — per NCIT
Also identified as
- ATC N05AH02 per RXNORM
- NCIT NCIT:C28936 per NCIT
- SCTID 387568001 per RXNORM
- SCTID 96221003 per RXNORM
- UNII J60AR2IKIC per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Bipolar disorder | may treat | MEDRT · Public domain (U.S. Government work) |