Danazol
Danazol
Definition
A synthetic androgen derived from ethinyl testosterone. Danazol indirectly reduces estrogen production by decreasing pituitary secretion of follicle-stimulating hormone and luteinizing hormone, and binds to sex hormone receptors in target tissues, thereby exhibiting antiestrogenic, anabolic and weakly androgenic effects. (NCI04)
Also known as (17Alpha)-pregna-2,4-dien-20-yno[2,3-d]-isoxazol-17-ol, (17alpha)-Pregna-2,4-dien-20-yno[2,3-d]isoxazol-17-ol, 1-Ethynyl-2,3,3a,3b,4,5,10,10a,10b,11,12,12a-dodecahydro-10a,12a-dimethyl-1H-cyclopental[7,8]phenanthro[3,2-d]isoxazol-1-ol, 17Alpha-ethynyl-17beta-hydroxy-4-androsteno[2,3-d]isoxazole, Bonzol, Chronogyn, Cyclomen, DAN, DANAZOL, Danocrine, Danol, Danoval, Ladogal, Win 17757, Win-17757, Winobanin — per NCIT
Also identified as
- ATC G03XA01 per RXNORM
- NCIT NCIT:C414 per NCIT
- SCTID 126124009 per RXNORM
- SCTID 87881000 per RXNORM
- UNII N29QWW3BUO per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Angioedema | may prevent | MEDRT · Public domain (U.S. Government work) |
| Breast fibrocystic disease | may treat | MEDRT · Public domain (U.S. Government work) |
| Endometriosis | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Breast | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Female reproductive system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Genitourinary system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Reproductive system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
4 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.