Prasterone
Prasterone
Definition
A synthetic form of dehydroepiandrosterone with potential chemopreventive activity. Produced endogenously, dehydroepiandrosterone (DHEA) is an intermediate in the conversion of cholesterol to androgens and estrogens. Although the mechanisms of action of exogenously administered DHEA have not been fully illuminated, they may result in both direct and indirect physiologic effects. Direct effects include GABA-a receptor complex and NMDA receptor modulation, and enhanced pancreatic beta cell insulin secretion and antiglucocorticoid activities. (NCI04)
Also known as 17-Hormoforin, 3beta-Hydroxyandrost-5-en-17-one, 5,6-Dehydroisoandrosterone, Dehydroepiandrosterone, Dehydroisoandrosterone, DHEA, Diandron, Fidelin, GL701, PRASTERONE, Therapeutic Dehydroepiandrosterone — per NCIT
Also identified as
- ATC A14AA07 per RXNORM
- ATC G03XX01 per RXNORM
- NCIT NCIT:C2265 per NCIT
- SCTID 413963008 per RXNORM
- SCTID 78316004 per RXNORM
- UNII 459AG36T1B per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Adrenocortical insufficiency | may treat | MEDRT · Public domain (U.S. Government work) |
| Lupus vulgaris | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Adrenal glands | may treat a disease of this organ | DERIVED · CC BY 4.0 |
1 entry above is marked DERIVED: Atlas Médico inferred it by combining two sourced claims, and no source asserts this link directly. Treat it as a navigation aid, not as a clinical statement.