Desoximetasone
Desoximetasone
Definition
A synthetic glucocorticoid receptor agonist with metabolic, anti-inflammatory and immunosuppressive activity. Desoximetasone activates specific intracellular receptors, which bind to distinct sites on DNA to modify gene transcription. This results in an induction of the synthesis of anti-inflammatory proteins and suppression of the synthesis of inflammatory mediators. This leads to an overall reduction in chronic inflammation and autoimmune reactions. Desoximetasone is indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Also known as 9-Fluoro-11-beta,21-dihydroxy-16-alpha-methylpregna-1,4-diene-3,20-dione, DESOXIMETASONE, Topicort, Topicort LP, Topsilon — per NCIT
Also identified as
- ATC D07AC03 per RXNORM
- ATC D07XC02 per RXNORM
- NCIT NCIT:C47477 per NCIT
- SCTID 387473009 per RXNORM
- SCTID 81457006 per RXNORM
- UNII 4E07GXB7AU per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Facial dermatosis | may treat | MEDRT · Public domain (U.S. Government work) |
| Hand dermatosis | may treat | MEDRT · Public domain (U.S. Government work) |
| Leg dermatosis | may treat | MEDRT · Public domain (U.S. Government work) |
| Scalp dermatosis | may treat | MEDRT · Public domain (U.S. Government work) |