Dibucaine
Dibucaine
Definition
A quinoline derivative and amino amide with anesthetic activity. Dibucaine reversibly binds to and inactivates sodium channels in the neuronal cell membrane. Inhibition of sodium channels prevents the depolarization of nerve cell membranes and inhibits subsequent propagation of impulses along the course of the nerve, thereby limiting the excitation of nerve endings. This results in loss of sensation.
Also known as Cinchocaine, DIBUCAINE — per NCIT
Also identified as
- ATC C05AD04 per RXNORM
- ATC D04AB02 per RXNORM
- ATC N01BB06 per RXNORM
- ATC S01HA06 per RXNORM
- ATC S02DA04 per RXNORM
- NCIT NCIT:C28984 per NCIT
- SCTID 349831001 per RXNORM
- SCTID 395953008 per RXNORM
- UNII L6JW2TJG99 per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Irritant dermatitis | may treat | MEDRT · Public domain (U.S. Government work) |
| Sunburn | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Skin of body | may treat a disease of this organ | DERIVED · CC BY 4.0 |
1 entry above is marked DERIVED: Atlas Médico inferred it by combining two sourced claims, and no source asserts this link directly. Treat it as a navigation aid, not as a clinical statement.