Dicloxacillin
Dicloxacillin
Definition
A broad-spectrum, semi-synthetic, beta-lactam, penicillin antibiotic with bactericidal and beta-lactamase resistant activity. Dicloxacillin binds to penicillin binding proteins (PBP) located on the inner membrane of the bacterial cell wall. It also inhibits the cross-linkage of peptidoglycan, a critical component of bacterial cell walls. This leads to the inhibition of bacterial cell wall synthesis and eventually causes cell lysis.
Also known as 3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolylpenicillin, DICLOXACILLIN — per NCIT
Also identified as
- ATC J01CF01 per RXNORM
- NCIT NCIT:C28986 per NCIT
- SCTID 372873001 per RXNORM
- SCTID 8416000 per RXNORM
- UNII COF19H7WBK per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Gram-positive bacterial infections | may prevent | MEDRT · Public domain (U.S. Government work) |
| Bacterial pneumonia | may treat | MEDRT · Public domain (U.S. Government work) |
| Cellulitis | may treat | MEDRT · Public domain (U.S. Government work) |
| Osteomyelitis | may treat | MEDRT · Public domain (U.S. Government work) |
| Urinary tract infection | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Bone element | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Lungs | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Musculoskeletal system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Respiratory system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
4 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.