Dipyridamole

Definition

A synthetic agent derivative of pyrimido-pyrimidine, with antiplatelet properties. Dipyridamole inhibits adenosine uptake by platelets and endothelial cells, triggering an accumulation of cyclic adenosine monophosphate (cAMP), and inhibiting the stimulation of platelet aggregation by agents such as platelet activating factor and collagen. (NCI04)

Also known as 2,2',2'',2''''-[(4,8-Dipiperidinopyrimido-[5,4-d]pyrimidine-2,6-diyl)dinitrilo]tetraethanol, DIPYRIDAMOLE, DP, Persantine — per NCIT

Also identified as

• ATC B01AC07 per RXNORM
• NCIT NCIT:C445 per NCIT
• SCTID 387371005 per RXNORM
• SCTID 66859009 per RXNORM
• UNII 64ALC7F90C per RXNORM

Indications