Ethinyl Estradiol

Ethinyl Estradiol

Definition

A semisynthetic estrogen. Ethinyl estradiol binds to the estrogen receptor complex and enters the nucleus, activating DNA transcription of genes involved in estrogenic cellular responses. This agent also inhibits 5-alpha reductase in epididymal tissue, which lowers testosterone levels and may delay progression of prostatic cancer. In addition to its antineoplastic effects, ethinyl estradiol protects against osteoporosis. In animal models, short-term therapy with this agent has been shown to provide long-term protection against breast cancer, mimicking the antitumor effects of pregnancy. (NCI04)

Also known as (17alpha)-19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol, Diogyn E, Diogyn-E, Estinyl, Ethinoral, ETHINYL ESTRADIOL, Ethinylestradiol, Eticylol, Feminone, Inestra, Lynoral, Orestralyn — per NCIT

Also identified as

Indications

Disease Relation Source
Postmenopausal osteoporosis may prevent MEDRT · Public domain (U.S. Government work)
Breast neoplasm may treat MEDRT · Public domain (U.S. Government work)
Hypogonadism may treat MEDRT · Public domain (U.S. Government work)
Premature menopause may treat MEDRT · Public domain (U.S. Government work)
Primary ovarian failure may treat MEDRT · Public domain (U.S. Government work)
Prostate cancer may treat MEDRT · Public domain (U.S. Government work)

Organ Effects

Organ Side effect / interaction Source
Female reproductive system may treat a disease of this organ DERIVED · CC BY 4.0
Genitourinary system may treat a disease of this organ DERIVED · CC BY 4.0
Gonad may treat a disease of this organ DERIVED · CC BY 4.0
Ovaries may treat a disease of this organ DERIVED · CC BY 4.0
Reproductive system may treat a disease of this organ DERIVED · CC BY 4.0

5 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.