Ethosuximide

ATC Code N03AD01

Ethosuximide

Definition

A succinimide with anticonvulsant activity. The exact mechanism of action is not entirely understood, but most likely ethosuximide exerts its effects by partial antagonism of T-type calcium channels of the thalamic neurons. This leads to a decrease in burst firing of thalamocortical neurons, which stabilizes the nerve activity in the brain and prevents seizures.

Also known as 3-Ethyl-3-methylpyrrolidine-2,5-dione, ETHOSUXIMIDE, Zarontin — per NCIT

Also identified as