Etomidate
Etomidate
Definition
An imidazole derivative with short-acting sedative, hypnotic, and general anesthetic properties. Etomidate appears to have gamma-aminobutyric acid (GABA) like effects, mediated through GABA-A receptor. The action enhances the inhibitory effect of GABA on the central nervous system by causing chloride channel opening events which leads to membrane hyperpolarization.
Also known as 1H-Imidazole-5-Carboxylic Acid, 1-((1R)-1-phenylethyl)-, Ethyl Ester, Amidate, ETOMIDATE, R-(+)-Ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate — per NCIT
Also identified as
- ATC N01AX07 per RXNORM
- NCIT NCIT:C47527 per NCIT
- SCTID 387218008 per RXNORM
- SCTID 40429005 per RXNORM
- UNII Z22628B598 per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Brain ischemia | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Brain | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Cardiovascular system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Central nervous system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Nervous system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
4 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.