Felodipine
ATC Code
C08CA02
Felodipine
Definition
A dihydropyridine calcium channel blocking agent. Felodipine inhibits the influx of extracellular calcium ions into myocardial and vascular smooth muscle cells, causing dilatation of the main coronary and systemic arteries and decreasing myocardial contractility. This agent also inhibits the drug efflux pump P-glycoprotein which is overexpressed in some multi-drug resistant tumors and may improve the efficacy of some antineoplastic agents. (NCI04)
Also known as FELODIPINE, Plendil — per NCIT
Also identified as
- ATC C08CA02 per RXNORM
- NCIT NCIT:C29046 per NCIT
- SCTID 108535009 per RXNORM
- SCTID 386863007 per RXNORM
- UNII OL961R6O2C per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Hypertensive disorder | may treat | MEDRT · Public domain (U.S. Government work) |
| Prinzmetal angina | may treat | MEDRT · Public domain (U.S. Government work) |