Fenfluramine

Definition

An amphetamine derivative and a sympathomimetic stimulant with appetite-suppressant property. Fenfluramine, which was part of the Fen-Phen anti-obesity medication, stimulates the release of serotonin from vesicular storage, and modulates serotonin transporter function. Since serotonin regulates mood and appetite, among other functions, increased serotonin level results in a feeling of fullness and loss of appetite.

Also known as 1-(meta-Trifluoromethyl-phenyl)-2 Ethylaminopropane, 2-Ethylamino-1-(3-trifluoromethylphenyl)propane, 3-(Trifluoromethyl)-N-ethyl-alpha-methylphenethylamine, FENFLURAMINE — per NCIT

Also identified as

• ATC A08AA02 per RXNORM
• ATC N03AX26 per RXNORM
• NCIT NCIT:C81418 per NCIT
• SCTID 387451002 per RXNORM
• SCTID 78700004 per RXNORM
• UNII 2DS058H2CF per RXNORM

Indications