Ganciclovir
Ganciclovir
Definition
A synthetic guanine derivative with antiviral activity. As the active metabolite of ganciclovir, ganciclovir-5-triphosphate (ganciclovir-TP) appears to inhibit viral DNA synthesis by competitive inhibition of viral DNA polymerases and incorporation into viral DNA, resulting in eventual termination of viral DNA elongation.
Also known as 2-Amino-1,9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-6H-purin-6-one, 2'-Nor-2'-deoxyguanosine, 2'NDG, 9-[(1,3-Dihydroxy-2-propoxy)methyl]guanine, Cymevan, DHPG, GANCICLOVIR, GCV, Nordeoxyguanosine, Virgan — per NCIT
Also identified as
- ATC J05AB06 per RXNORM
- ATC S01AD09 per RXNORM
- NCIT NCIT:C517 per NCIT
- SCTID 372848001 per RXNORM
- SCTID 76587005 per RXNORM
- SCTID 78025001 per RXNORM
- UNII P9G3CKZ4P5 per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Cytomegalovirus infection | may prevent | MEDRT · Public domain (U.S. Government work) |
| Cytomegalovirus retinitis | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Camera-type eye | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Retina | may treat a disease of this organ | DERIVED · CC BY 4.0 |
2 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.