Glycerin
Glycerin
Definition
A trihydroxyalcohol with localized osmotic diuretic and laxative effects. Glycerin elevates the blood plasma osmolality thereby extracting water from tissues into interstitial fluid and plasma. This agent also prevents water reabsorption in the proximal tubule in the kidney leading to an increase in water and sodium excretion and a reduction in blood volume. Administered rectally, glycerin exerts a hyperosmotic laxative effect by attracting water into the rectum, thereby relieving constipation. In addition, glycerin is used as a solvent, humectant and vehicle in various pharmaceutical preparations.
Also known as 1,2,3-Propanetriol, GLYCERIN, Glycerol — per NCIT
Also identified as
- ATC A06AG04 per RXNORM
- ATC A06AX01 per RXNORM
- NCIT NCIT:C29077 per NCIT
- SCTID 404833002 per RXNORM
- SCTID 80582002 per RXNORM
- UNII PDC6A3C0OX per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Dermatitis | may prevent | MEDRT · Public domain (U.S. Government work) |
| Constipation disorder | may treat | MEDRT · Public domain (U.S. Government work) |
| Dermatitis | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Skin of body | may treat a disease of this organ | DERIVED · CC BY 4.0 |
1 entry above is marked DERIVED: Atlas Médico inferred it by combining two sourced claims, and no source asserts this link directly. Treat it as a navigation aid, not as a clinical statement.