Recombinant Thyrotropin Alfa
Recombinant Thyrotropin Alfa
Definition
A recombinant form of the human anterior pituitary glycoprotein thyroid stimulating hormone (TSH) with use in the diagnostic setting. With an amino acid sequence identical to that of human TSH, thyrotropin alfa binds to TSH receptors on normal thyroid epithelial cells or well-differentiated thyroid cancer cells, stimulating iodine uptake and organification, synthesis and secretion of thyroglobulin (Tg), triiodothyronine (T3), and thyroxine (T4).
Also known as Recombinant Thyrotropin Alfa, Recombinant Thyrotropin Alpha, Recombinant TSH Alpha, Thyrogen, Thyroid Stimulating Hormone Alpha, THYROTROPIN ALFA, TSH-alpha — per NCIT
Also identified as
- ATC H01AB01 per RXNORM
- NCIT NCIT:C61322 per NCIT
- SCTID 407733000 per RXNORM
- SCTID 412520006 per RXNORM
- UNII AVX3D5A4LM per RXNORM