Halcinonide

Definition

A topical, synthetic glucocorticoid with anti-inflammatory and anti-allergic properties. Halcinonide exerts its effect by interacting with specific intracellular receptors, and the ligand-receptor complex subsequently modulates gene expressions via the typical glucocorticoid signalling pathway. This results in the synthesis of certain anti-inflammatory proteins as well as in synthesis inhibition of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions are accomplished. (NCI05)

Also known as 21-Chloro-9-fluoro-11beta,16alpha,17-trihydroxypregn-4-ene-3,20-dione Cyclic 16,17-Acetal with Acetone, Halciderm, HALCINONIDE, Halcort, Halog, Pregn-4-ene-3,20-dione, 21-chloro-9-fluoro-11-hydroxy-16,17-((1-methylethylidene)bis(oxy))-,(11beta,16alpha)-, Volog — per NCIT

Also identified as

• ATC D07AD02 per RXNORM
• NCIT NCIT:C47552 per NCIT
• SCTID 29058003 per RXNORM
• SCTID 395735005 per RXNORM
• UNII SI86V6QNEG per RXNORM

Indications