Metformin

Definition

An agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity. Metformin is associated with a very low incidence of lactic acidosis. This agent helps reduce LDL cholesterol and triglyceride levels, and is not associated with weight gain, and prevents the cardiovascular complications of diabetes. Metformin is not metabolized and is excreted unchanged by the kidneys.

NCIT:C61612 · NCI Thesaurus OBO Edition · CC BY 4.0

Also known as 1,1-Dimethylbiguanide, METFORMIN, N,N-dimethylbiguanide, N,N-Dimethylimidodicarbonimidic Diamide — per NCIT

Also identified as

ATC A10BA per NCIT
ATC A10BD per NCIT
NCIT NCIT:C61612 per NCIT

Indications

Disease	Relation	Source
Diabetes mellitus type 2	may treat	MEDRT · Public domain (U.S. Government work)

Organ Effects

Organ	Side effect / interaction	Source
Alimentary part of gastrointestinal system	may treat a disease of this organ	DERIVED · CC BY 4.0
Pancreas	may treat a disease of this organ	DERIVED · CC BY 4.0

2 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.