Ketoprofen
Ketoprofen
Definition
A propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic effects. Ketoprofen inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis, by prostaglandin synthase, is responsible for the therapeutic effects of ibuprofen. Ketoprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation.
Also known as Benzeneacetic Acid, 3-benzoyl-alpha-methyl-, Capisten, KETOPROFEN, Orudis, Oruvail, Propionic Acid, 2-(3-benzoylphenyl)- — per NCIT
Also identified as
- ATC M01AE03 per RXNORM
- ATC M02AA10 per RXNORM
- NCIT NCIT:C47578 per NCIT
- SCTID 10099000 per RXNORM
- SCTID 386832008 per RXNORM
- UNII 90Y4QC304K per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Osteoarthritis | may treat | MEDRT · Public domain (U.S. Government work) |
| Rheumatoid arthritis | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Bone element | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Musculoskeletal system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Skeletal joint | may treat a disease of this organ | DERIVED · CC BY 4.0 |
3 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.