Methoxsalen

Methoxsalen

Definition

A naturally occurring substance isolated from the seeds of the plant Ammi majus with photoactivating properties. As a member of the family of compounds known as psoralens or furocoumarins, methoxsalen's exact mechanism of action is unknown; upon photoactivation, methoxsalen has been observed to bind covalently to and crosslink DNA. (NCI04)

Also known as 8-Methoxypsoralen, 8-MOP, 9-Methoxy-7H-furo[3,2-g][1]benzopyran-7-one, Ammoidin, Deltasoralen, Dermox, Geralen, Geroxalen, Meladinina, Meladinine, METHOXSALEN, Methoxypsoralen, Metoxaleno, Mopsoralen, Oxsoralen, Oxsoralen-Ultra, Puvasoralen, Ultramop, Uvadex, XANTHOTOXIN — per NCIT

Also identified as

Indications

Disease Relation Source
Mycosis fungoides may treat MEDRT · Public domain (U.S. Government work)
Psoriasis may treat MEDRT · Public domain (U.S. Government work)
Vitiligo may treat MEDRT · Public domain (U.S. Government work)

Organ Effects

Organ Side effect / interaction Source
Lymphoid system may treat a disease of this organ DERIVED · CC BY 4.0
Skin of body may treat a disease of this organ DERIVED · CC BY 4.0

2 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.