Omeprazole

ATC Code A02BC01

Omeprazole

Definition

A benzimidazole with selective and irreversible proton pump inhibition activity. Omeprazole forms a stable disulfide bond with the sulfhydryl group of the hydrogen-potassium (H+ - K+) ATPase found on the secretory surface of parietal cells, thereby inhibiting the final transport of hydrogen ions (via exchange with potassium ions) into the gastric lumen and suppressing gastric acid secretion. This agent exhibits no anticholinergic activities and does not antagonize histamine H2 receptors.

Also known as 5-Methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl)-1H-benzimidazole, H168/68, Losec, OMEP, OMEPRAZOLE, Prilosec — per NCIT

Also identified as

Indications

Disease Relation Source
Duodenal ulcer may treat MEDRT · Public domain (U.S. Government work)
Esophagitis may treat MEDRT · Public domain (U.S. Government work)
Gastric ulcer may treat MEDRT · Public domain (U.S. Government work)
Gastroesophageal reflux disease may treat MEDRT · Public domain (U.S. Government work)
Helicobacter pylori infectious disease may treat MEDRT · Public domain (U.S. Government work)
Zollinger-Ellison syndrome may treat MEDRT · Public domain (U.S. Government work)

Organ Effects

Organ Side effect / interaction Source
Alimentary part of gastrointestinal system may treat a disease of this organ DERIVED · CC BY 4.0
Esophagus may treat a disease of this organ DERIVED · CC BY 4.0
Intestine may treat a disease of this organ DERIVED · CC BY 4.0
Small intestine may treat a disease of this organ DERIVED · CC BY 4.0
Stomach may treat a disease of this organ DERIVED · CC BY 4.0
Upper digestive tract may treat a disease of this organ DERIVED · CC BY 4.0

6 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.