Mifepristone
Mifepristone
Definition
A derivative of the synthetic progestin norethindrone with antiprogesterone activity. Mifepristone competitively binds to the progesterone receptor, resulting in inhibition of the effects of endogenous or exogenous progesterone. This agent also exhibits antiglucocorticoid and weak antiandrogenic activities.
Also known as (aa Beta, 17 beta)-11-[4-(dimethylamino)-phenyl]-17-hydroxy-17-(1-propynyl)estra-4,9-dien-3-one, 11 Beta-[4-(N,N-dimethylamino)phenyl]-17alpha-(propyl-1-ynyl)-delta-4,9-estradiene-17 beta-ol-3-one, 11-((4-dimethylamino) phenyl)-17-Hydroxy-17-(1-propynyl) Estra-4,9- dien-3-one, Korlym, Mifegyne, Mifeprex, MIFEPRISTONE, RU 486, RU-38486, RU-486 — per NCIT
Also identified as
- ATC G03XB01 per RXNORM
- NCIT NCIT:C655 per NCIT
- SCTID 129483007 per RXNORM
- SCTID 395796009 per RXNORM
- UNII 320T6RNW1F per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Brain cancer | may treat | MEDRT · Public domain (U.S. Government work) |
| Ectopic pregnancy | may treat | MEDRT · Public domain (U.S. Government work) |
| Hyperglycemia | may treat | MEDRT · Public domain (U.S. Government work) |