Mycophenolic Acid

ATC Code L04AA06

Mycophenolic Acid

Definition

An antineoplastic antibiotic derived from various Penicillium fungal species. Mycophenolic acid is an active metabolite of the prodrug mycophenolate mofetil. Mycophenolic acid inhibits inosine monophosphate dehydrogenase (IMPDH), preventing the formation of guanosine monophosphate and synthesis of lymphocyte DNA that results in inhibition of lymphocyte proliferation, antibody production, cellular adhesion, and migration of T and B lymphocytes. Mycophenolic acid also has antibacterial, antifungal, and antiviral activities. (NCI04)

Also known as 4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, (E)-, 4-Hexenoic acid, 6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-, (E)-, Acide mycophenolique, Acido micofenolico, Acidum mycophenolicum, Lilly-68618, Ly 68618, MPA, MYCOPHENOLIC ACID, Myfortic — per NCIT

Also identified as

Indications

Disease Relation Source
Graft versus host disease may prevent MEDRT · Public domain (U.S. Government work)
Graft versus host disease may treat MEDRT · Public domain (U.S. Government work)
Psoriasis may treat MEDRT · Public domain (U.S. Government work)

Organ Effects

Organ Side effect / interaction Source
Skin of body may treat a disease of this organ DERIVED · CC BY 4.0

1 entry above is marked DERIVED: Atlas Médico inferred it by combining two sourced claims, and no source asserts this link directly. Treat it as a navigation aid, not as a clinical statement.