Nifedipine
ATC Code
C08CA05
Nifedipine
Definition
A dihydropyridine calcium channel blocking agent. Nifedipine inhibits the transmembrane influx of extracellular calcium ions into myocardial and vascular smooth muscle cells, causing dilatation of the main coronary and systemic arteries and decreasing myocardial contractility. This agent also inhibits the drug efflux pump P-glycoprotein which is overexpressed in some multi-drug resistant tumors and may improve the efficacy of some antineoplastic agents. (NCI04)
Also known as Adalat, NIFEDIPINE, Procardia — per NCIT
Also identified as
- ATC C08CA05 per RXNORM
- NCIT NCIT:C29290 per NCIT
- SCTID 387490003 per RXNORM
- SCTID 85272000 per RXNORM
- UNII I9ZF7L6G2L per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Hypertensive disorder | may treat | MEDRT · Public domain (U.S. Government work) |
| Prinzmetal angina | may treat | MEDRT · Public domain (U.S. Government work) |