Nisoldipine
ATC Code
C08CA07
Nisoldipine
Definition
A dihydropyridine calcium channel blocking agent. Nisoldipine inhibits the transmembrane influx of extracellular calcium ions into myocardial and vascular smooth muscle cells, causing dilatation of the main coronary and systemic arteries and decreasing myocardial contractility. This agent also inhibits the drug efflux pump P-glycoprotein which is overexpressed in some multi-drug resistant tumors and may improve the efficacy of some antineoplastic agents. (NCI04)
Also known as NISOLDIPINE, Nisoldipine SR, Sular — per NCIT
Also identified as
- ATC C08CA07 per RXNORM
- NCIT NCIT:C29291 per NCIT
- SCTID 108524004 per RXNORM
- SCTID 386861009 per RXNORM
- UNII 4I8HAB65SZ per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Hypertensive disorder | may treat | MEDRT · Public domain (U.S. Government work) |
| Prinzmetal angina | may treat | MEDRT · Public domain (U.S. Government work) |