Orphenadrine
Orphenadrine
Definition
A muscarinic antagonist with muscle relaxant activity. Although the mechanism of action has not been determined, orphenadrine appears to block muscarinic acetylcholine receptors as well as N-methyl-D-aspartate (NMDA) receptors in the central nervous system (CNS). This may interfere with the transmission of nerve impulses from the spinal cord to the muscles and may help relax muscles. In addition, orphenadrine exerts antagonistic effects on histamine H1 receptors.
Also known as ORPHENADRINE — per NCIT
Also identified as
- NCIT NCIT:C61868 per NCIT
- SCTID 35035001 per RXNORM
- SCTID 372714007 per RXNORM
- UNII AL805O9OG9 per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Myositis disease | may treat | MEDRT · Public domain (U.S. Government work) |
| Tetanus | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Musculature | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Musculoskeletal system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
2 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.