Oxacillin
ATC Code
J01CF04
Oxacillin
Definition
A semisynthetic penicillinase-resistant and acid-stable penicillin with an antimicrobial activity. Oxacillin binds to penicillin-binding proteins in the bacterial cell wall, thereby blocking the synthesis of peptidoglycan, a critical component of the bacterial cell wall. This leads to inhibition of cell growth and causes cell lysis.
Also known as OXACILLIN — per NCIT
Also identified as
- ATC J01CF04 per RXNORM
- NCIT NCIT:C62063 per NCIT
- SCTID 372868007 per RXNORM
- SCTID 83201006 per RXNORM
- SCTID 85724000 per RXNORM
- UNII UH95VD7V76 per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Gram-positive bacterial infections | may prevent | MEDRT · Public domain (U.S. Government work) |
| Bacterial endocarditis | may treat | MEDRT · Public domain (U.S. Government work) |
| Bacterial meningitis | may treat | MEDRT · Public domain (U.S. Government work) |
| Cellulitis | may treat | MEDRT · Public domain (U.S. Government work) |
| Osteomyelitis | may treat | MEDRT · Public domain (U.S. Government work) |
| Respiratory tract infectious disorder | may treat | MEDRT · Public domain (U.S. Government work) |
| Staphylococcal infection | may treat | MEDRT · Public domain (U.S. Government work) |
| Urinary tract infection | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Bone element | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Cardiovascular system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Central nervous system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Endocardium | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Heart | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Meninx | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Musculoskeletal system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Nervous system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
8 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.