Papaverine
Papaverine
Definition
An opiate alkaloid isolated from the plant Papaver somniferum and produced synthetically. As a direct-acting smooth muscle relaxant, papaverine is not closely related to the other opium alkaloids in structure or pharmacological actions; its mechanism of action may involve the non-selective inhibition of phosphodiesterases and direct inhibition of calcium channels. This agent also exhibits antiviral activity against respiratory syncytial virus, cytomegalovirus, and HIV. (NCI04)
Also known as Cerebid, Cerespan, PAPAVERINE, Pavabid, Pavacap, Pavatym, Robaxapap — per NCIT
Also identified as
- ATC A03AD01 per RXNORM
- ATC G04BE02 per RXNORM
- NCIT NCIT:C726 per NCIT
- SCTID 372784001 per RXNORM
- SCTID 58467001 per RXNORM
- UNII DAA13NKG2Q per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Brain ischemia | may treat | MEDRT · Public domain (U.S. Government work) |
| Erectile dysfunction | may treat | MEDRT · Public domain (U.S. Government work) |
| Pulmonary embolism | may treat | MEDRT · Public domain (U.S. Government work) |
| Raynaud disease | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Brain | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Cardiovascular system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Central nervous system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Nervous system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
4 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.