Penicillin G

Penicillin G

Definition

A broad-spectrum, beta-lactam naturally occurring penicillin antibiotic with antibacterial activity. Penicillin G binds to and inactivates the penicillin binding proteins (PBPs) located inside the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall and eventually causing cell lysis.

Also known as PENICILLIN G — per NCIT

Also identified as

Indications

Disease Relation Source
Bacterial infectious disease may prevent MEDRT · Public domain (U.S. Government work)
Actinomycosis may treat MEDRT · Public domain (U.S. Government work)
Anthrax may treat MEDRT · Public domain (U.S. Government work)
Botulism may treat MEDRT · Public domain (U.S. Government work)
Diphtheria may treat MEDRT · Public domain (U.S. Government work)
Empyema may treat MEDRT · Public domain (U.S. Government work)
Endocarditis may treat MEDRT · Public domain (U.S. Government work)
Erysipelothrix infectious disease may treat MEDRT · Public domain (U.S. Government work)
Escherichia coli infection may treat MEDRT · Public domain (U.S. Government work)
Gonorrhea may treat MEDRT · Public domain (U.S. Government work)
Listeriosis may treat MEDRT · Public domain (U.S. Government work)
Meningococcal infection may treat MEDRT · Public domain (U.S. Government work)
Pasteurellosis may treat MEDRT · Public domain (U.S. Government work)
Pericarditis may treat MEDRT · Public domain (U.S. Government work)
Pneumococcal infection may treat MEDRT · Public domain (U.S. Government work)
Rat-bite fever may treat MEDRT · Public domain (U.S. Government work)
Respiratory tract infectious disorder may treat MEDRT · Public domain (U.S. Government work)
Rheumatic fever may treat MEDRT · Public domain (U.S. Government work)
Salmonellosis may treat MEDRT · Public domain (U.S. Government work)
Skin disease caused by bacterial infection may treat MEDRT · Public domain (U.S. Government work)
Staphylococcal infection may treat MEDRT · Public domain (U.S. Government work)
Subacute bacterial endocarditis may treat MEDRT · Public domain (U.S. Government work)
Syphilis may treat MEDRT · Public domain (U.S. Government work)
Tetanus may treat MEDRT · Public domain (U.S. Government work)
Urinary tract infection may treat MEDRT · Public domain (U.S. Government work)

Organ Effects

Organ Side effect / interaction Source
Cardiovascular system may treat a disease of this organ DERIVED · CC BY 4.0
Endocardium may treat a disease of this organ DERIVED · CC BY 4.0
Heart may treat a disease of this organ DERIVED · CC BY 4.0
Pericardium may treat a disease of this organ DERIVED · CC BY 4.0

4 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.