Phentermine

ATC Code A08AA01

Phentermine

Definition

A natural monoamine alkaloid derivative and a sympathomimetic stimulant with appetite suppressant property. Phentermine, which was part of the Fen-Phen anti-obesity medication, stimulates hypothalamic release of norepinephrine, a neurotransmitter involved in stress responses (fight-or-flight reactions), and reduces hunger sensation. Phentermine also causes the release of epinephrine or adrenaline outside of the brain, resulting in breakdown of stored fat.

Also known as 1,1-Dimethyl-2-phenylethylamine, 2-Amino-2-methyl-1-phenylpropane, 2-Phenyl-tert-butylamine, PHENTERMINE — per NCIT

Also identified as