Piperacillin
Piperacillin
Definition
A broad-spectrum semisynthetic, ampicillin-derived ureidopenicillin antibiotic. Piperacillin binds to penicillin binding proteins (PBP), the enzymes that catalyze the synthesis of peptidoglycan, a critical component of the bacterial cell wall. This blockade leads to the interruption of cell wall synthesis, consequently, leading to bacterial cell growth inhibition and cell lysis.
Also known as (2S,5R,6R)-6-((R)-2-(4-Ethyl-2,3-dioxo-1-piperazinecarboxamido)-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid Monohydrate, PIPERACILLIN — per NCIT
Also identified as
- ATC J01CA12 per RXNORM
- NCIT NCIT:C62069 per NCIT
- SCTID 372836004 per RXNORM
- SCTID 74575000 per RXNORM
- UNII X00B0D5O0E per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Escherichia coli infection | may treat | MEDRT · Public domain (U.S. Government work) |
| Pneumonia | may treat | MEDRT · Public domain (U.S. Government work) |
| Proteus infectious disease | may treat | MEDRT · Public domain (U.S. Government work) |
| Pseudomonas infection | may treat | MEDRT · Public domain (U.S. Government work) |
| Skin disorder caused by infection | may treat | MEDRT · Public domain (U.S. Government work) |
| Streptococcal infection | may treat | MEDRT · Public domain (U.S. Government work) |
| Urinary tract infection | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Lungs | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Respiratory system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
2 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.