Povidone-Iodine

Definition

An iodophor solution containing a water-soluble complex of iodine and polyvinylpyrrolidone (PVP) with broad microbicidal activity. Free iodine, slowly liberated from the polyvinylpyrrolidone iodine (PVPI) complex in solution, kills eukaryotic or prokaryotic cells through iodination of lipids and oxidation of cytoplasmic and membrane compounds. This agent exhibits a broad range of microbicidal activity against bacteria, fungi, protozoa, and viruses. Slow release of iodine from the PVPI complex in solution minimizes iodine toxicity towards mammalian cells.

Also known as Betadine, E-Z Prep, E-Z Scrub, Iodine Povidone Topical, Iodopovidone, Povidone iodine, POVIDONE-IODINE, Povidone-Iodine Solution, PVP iodine, PVP-I, PVP-Iodine, Traumasept, Ultradine, Videne — per NCIT

Also identified as

• ATC D08AG02 per RXNORM
• ATC D09AA09 per RXNORM
• ATC D11AC06 per RXNORM
• ATC G01AX11 per RXNORM
• ATC R02AA15 per RXNORM
• ATC S01AX18 per RXNORM
• NCIT NCIT:C766 per NCIT
• SCTID 111144003 per RXNORM
• SCTID 386989006 per RXNORM
• UNII 85H0HZU99M per RXNORM

Indications