Primaquine
ATC Code
P01BA03
Primaquine
Definition
A synthetic, 8-aminoquinoline derivative with antimalarial properties. Although its mechanism of action is unclear, primaquine bind to and alter the properties of protozoal DNA. This agent eliminates tissue (exo-erythrocytic) malarial infection, preventing the development of the erythrocytic forms of the parasite which are responsible for relapses in Plasmodium vivax and ovale malaria. Primaquine is active against late hepatic stages (hypnozoites, schizonts). (NCI04)
Also known as PRIMAQUINE — per NCIT
Also identified as
- ATC P01BA03 per RXNORM
- NCIT NCIT:C62071 per NCIT
- SCTID 36391008 per RXNORM
- SCTID 429663004 per RXNORM
- UNII MVR3634GX1 per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Plasmodium vivax malaria | may prevent | MEDRT · Public domain (U.S. Government work) |
| Plasmodium falciparum malaria | may treat | MEDRT · Public domain (U.S. Government work) |
| Plasmodium vivax malaria | may treat | MEDRT · Public domain (U.S. Government work) |