Prochlorperazine
Prochlorperazine
Definition
A synthetic propylpiperazine derivative of phenothiazine with antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Prochlorperazine antagonizes the dopamine D2-receptor in the chemoreceptor trigger zone (CTZ) of the brain and may prevent chemotherapy-induced emesis. (NCI04)
Also known as 2-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)-phenothiazine, Compro, PROCHLORPERAZINE, RP 6140, SKF-4657 — per NCIT
Also identified as
- ATC N05AB04 per RXNORM
- NCIT NCIT:C774 per NCIT
- SCTID 372853006 per RXNORM
- SCTID 79129001 per RXNORM
- UNII YHP6YLT61T per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Anxiety disorder | may treat | MEDRT · Public domain (U.S. Government work) |
| Dementia | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Central nervous system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Nervous system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
2 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.