Therapeutic Progesterone

ATC Code G03DA04

Therapeutic Progesterone

Definition

The therapeutic form of the naturally occurring hormone progesterone. Progesterone binds to the progesterone receptor, resulting in dissociation of heat shock proteins, receptor phosphorylation, and transcription activation through direct or indirect interaction with transcription factors. This agent exerts inhibitory effects on estrogens by decreasing the number of estrogen receptors and increasing its metabolism to inactive metabolites. Progesterone induces secretory changes in the endometrium, decreases uterine contractility during pregnancy, and maintains pregnancy.

Also known as 17alpha-Hydroxy-6alpha-methylpregn-4-ene-3,20-dione, Corlutina, Corluvite, Corpus luteum hormone, Cyclogest, Delta4-pregnene-3,20-dione, Gestiron, Gestone, Lipo-Lutin, Luteohormone, Lutocyclin, Lutocylin M, Lutogyl, Lutromone, Progestasert, PROGESTERONE, Progestin, Progestogel, Progestol, Progeston, Prolidon, Proluton, Syngesterone, Therapeutic Progesterone, Utrogestan — per NCIT

Also identified as