Promethazine
Promethazine
Definition
A phenothiazine derivative with antiemetic and antihistaminic properties. Promethazine antagonizes the central and peripheral effects of histamine mediated by histamine H1 receptors. The effects include bronchoconstriction, vasodilation and spasmodic contractions of gastrointestinal smooth muscle. In addition, this agent binds to muscarinic receptors, resulting in anticholinergic and antiemetic activities.
Also known as PROMETHAZINE — per NCIT
Also identified as
- ATC D04AA10 per RXNORM
- ATC R06AD02 per RXNORM
- NCIT NCIT:C779 per NCIT
- SCTID 372871004 per RXNORM
- SCTID 8372007 per RXNORM
- UNII FF28EJQ494 per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Anaphylaxis | may treat | MEDRT · Public domain (U.S. Government work) |
| Motion sickness | may treat | MEDRT · Public domain (U.S. Government work) |
| Perennial allergic rhinitis | may treat | MEDRT · Public domain (U.S. Government work) |
| Urticaria | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Craniocervical region | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Nasal cavity | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Skin of body | may treat a disease of this organ | DERIVED · CC BY 4.0 |
3 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.