Rimantadine
ATC Code
J05AC02
Rimantadine
Definition
A cyclic amine and alpha-methyl derivative of amantadine with antiviral activity. Although the exact mechanism of action of rimantadine is not understood, this agent appears to exert its antiviral effect against influenza A virus by interfering with the function of the transmembrane domain of the viral M2 protein, thereby preventing the uncoating of the virus and subsequent release of infectious viral nucleic acids into the cytoplasm of infected cells.
Also known as 1-(1-Adamantyl)ethylamin, alpha-Methyl-1-adamantanemethylamine, HSDB 7438, RIMANTADINE, Tricyclo(3.3.1.1(sup 3,7))decane-1-methanamine, alpha-methyl- — per NCIT
Also identified as
- ATC J05AC02 per RXNORM
- NCIT NCIT:C61927 per NCIT
- SCTID 108712009 per RXNORM
- SCTID 372532009 per RXNORM
- UNII 0T2EF4JQTU per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Influenza | may prevent | MEDRT · Public domain (U.S. Government work) |
| Influenza | may treat | MEDRT · Public domain (U.S. Government work) |