Talc

Definition

Finely-powdered native hydrous magnesium silicate. When administered into the pleural space, talc initiates an inflammatory reaction, resulting in adhesion of the visceral pleura to the parietal pleura and fibrosis, thereby effectively closing the pleural space and preventing further accumulation of fluid. This agent exhibits no intrinsic antineoplastic activity. (NCI04)

Also known as Sclerosol Intrapleural Aerosol, Sterile Talc Powder, Steritalc, TALC — per NCIT

Also identified as

• NCIT NCIT:C854 per NCIT
• SCTID 1557002 per RXNORM
• SCTID 409109009 per RXNORM
• UNII 7SEV7J4R1U per RXNORM

Indications