Temazepam
ATC Code
N05CD07
Temazepam
Definition
A benzodiazepine derivative with antidepressant, sedative, hypnotic and anticonvulsant properties. Temazepam potentiates the inhibitory activities of gamma-aminobutyric acid (GABA) by binding to the GABA receptor, located in the limbic, neocortical and mesencephalic reticular system. This increases the frequency of chloride channel opening events, allowing the flow of chloride ions into the neuron leading to membrane hyperpolarization and decreases neuronal excitability.
Also known as 10-chloro-4-hydroxy-6-methyl-2-phenyl-3,6-diazabicyclo[5.4.0]undeca-2,8,10,12-tetraen-5-one, Oxydiazepam, Ro 5-5345, TEMAZEPAM — per NCIT
Also identified as
- ATC N05CD07 per RXNORM
- NCIT NCIT:C29488 per NCIT
- SCTID 387300007 per RXNORM
- SCTID 54705000 per RXNORM
- UNII CHB1QD2QSS per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Depressive disorder | may treat | MEDRT · Public domain (U.S. Government work) |
| Insomnia | may treat | MEDRT · Public domain (U.S. Government work) |
| Panic disorder | may treat | MEDRT · Public domain (U.S. Government work) |