Trifluridine

Definition

A fluorinated thymidine analog with potential antineoplastic activity. Trifluridine is incorporated into DNA and inhibits thymidylate synthase, resulting in inhibition of DNA synthesis, inhibition of protein synthesis, and apoptosis. This agent also exhibits antiviral activity. (NCI04)

Also known as 2'-Deoxy-5-trifluoromethyluridine, F3TdR, Triflorothymidine, TRIFLURIDINE — per NCIT

Also identified as

• ATC S01AD02 per RXNORM
• NCIT NCIT:C905 per NCIT
• SCTID 373512003 per RXNORM
• SCTID 58892008 per RXNORM
• UNII RMW9V5RW38 per RXNORM