Urea
Urea
Definition
A nitrogenous compound containing a carbonyl group attached to two amine groups with osmotic diuretic activity. In vivo, urea is formed in the liver via the urea cycle from ammonia and is the final end product of protein metabolism. Administration of urea elevates blood plasma osmolality, resulting in enhanced flow of water from tissues, including the brain, cerebrospinal fluid and eye, into interstitial fluid and plasma, thereby decreasing pressure in those tissues and increasing urine outflow.
Also known as Aqua Care, Carbamide, Elaqua XX, Lanaphilic, Nutraplus, UREA, Ureaphil, Vanamide — per NCIT
Also identified as
- ATC B05BC02 per RXNORM
- ATC D02AE01 per RXNORM
- NCIT NCIT:C29531 per NCIT
- SCTID 16858004 per RXNORM
- SCTID 387092000 per RXNORM
- UNII 8W8T17847W per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Epidermolytic ichthyosis | may treat | MEDRT · Public domain (U.S. Government work) |
| Intracranial hypertension | may treat | MEDRT · Public domain (U.S. Government work) |
| Ocular hypertension | may treat | MEDRT · Public domain (U.S. Government work) |