Cobalamin
Cobalamin
Definition
An essential nutrient and natural water-soluble vitamin of the B-complex family that must combine with an intrinsic factor for absorption by the intestine, Vitamin B12 (cyanocobalamin) is necessary for hematopoiesis, neural metabolism, DNA and RNA production, and carbohydrate, fat, and protein metabolism. B12 improves iron functions in the metabolic cycle and assists folic acid in choline synthesis. B12 metabolism is interconnected with that of folic acid. Vitamin B12 deficiency causes pernicious anemia, megaloblastic anemia, and neurologic lesions.
Also known as B12 Vitamin, COBALAMIN, Cobalamin (1+), VIT B12, Vitamin B-12, Vitamin B12, Vitamin-B12 — per NCIT
Also identified as
- ATC B03BA01 per RXNORM
- NCIT NCIT:C939 per NCIT
- SCTID 30010009 per RXNORM
- SCTID 304111003 per RXNORM
- SCTID 419382002 per RXNORM
- UNII 8406EY2OQA per RXNORM
- UNII P6YC3EG204 per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Vitamin B12 deficiency | may prevent | MEDRT · Public domain (U.S. Government work) |
| Alcoholic polyneuropathy | may treat | MEDRT · Public domain (U.S. Government work) |
| Diabetic neuropathy | may treat | MEDRT · Public domain (U.S. Government work) |
| Multiple sclerosis | may treat | MEDRT · Public domain (U.S. Government work) |
| Pernicious anemia | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Central nervous system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Nervous system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
2 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.