Fomepizole
ATC Code
V03AB34
Fomepizole
Definition
A pyrazole with competitive alcohol dehydrogenase inhibitor activity. Fomepizole prevents the metabolism of ethylene glycol and methanol by alcohol dehydrogenase, thereby inhibiting the formation of their toxic metabolites, glycolate and oxalate (from ethylene glycol), and formic acid (from methanol). Fomepizole is indicated for use as an antidote in ethylene glycol and methanol poisoning. (NCI05)
Also known as 1H-Pyrazole, 4-methyl-, 4-Methylpyrazol, Antizol, FOMEPIZOLE — per NCIT
Also identified as
- ATC V03AB34 per RXNORM
- NCIT NCIT:C47538 per NCIT
- SCTID 109100006 per RXNORM
- SCTID 386970006 per RXNORM
- UNII 83LCM6L2BY per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Kidney failure | may prevent | MEDRT · Public domain (U.S. Government work) |
| Vision disorder | may prevent | MEDRT · Public domain (U.S. Government work) |